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Gluten Intolerance Prevalent Around the World

Published date: July 21, 2013 | Modified date:
by Dr Stephen Wangen
(photo: commons.wikimedia)
(photo: commons.wikimedia)

This is a reminder that gluten intolerance is found throughout the world.  And while there are fewer cases in Asia and Africa, there is also less testing for it in those parts of the world.

This is also a lesson that gluten intolerance is not just caused by the type of wheat that we eat in this country. Other countries with other types of wheat also experience a significant amount of gluten intolerance.

Study from National Institutes of Health:

Systematic review: Worldwide Variation in the Frequency of Coeliac Disease and Changes Over Time.
Kang JY, Kang AH, Green A, Gwee KA, Ho KY.

Department of Gastroenterology, St George’s Hospital, London, UK.

Coeliac disease (CD), originally thought to be largely confined to Northern Europe and Australasia and uncommon in North America and the Middle East, is now recognised to be equally common in all these countries. It is still thought to be rare in the Orient and Sub-Saharan Africa.

To assess geographical differences and time trends in the frequency of CD.

Medline and Embase searches were conducted on 10 November 2012, from 1946 and 1980 respectively, using the key words: coeliac disease or celiac disease + prevalence or incidence or frequency.

There were significant intra- and inter-country differences in the prevalence and incidence of CD. Only 24 ethnic Chinese and Japanese patients have been reported in the English literature. Of CD-associated HLA DQ antigens, DQ2 occurs in 5-10% of Chinese and sub-Saharan Africans, compared to 5-20% in Western Europe. DQ8 occurs in 5-10% of English, Tunisians and Iranians, but in <5% of Eastern Europeans, Americans and Asians. The prevalence and incidence of both clinically and serologically diagnosed CD increased in recent years. These geographical and temporal differences seem genuine, although variable indices of suspicion and availability of diagnostic facilities are confounding factors.

Coeliac disease is increasing in frequency, with significant geographical differences. Although few cases have been described to date in the Orient and Sub-Saharan Africa, there is a significant prevalence of HLA DQ2 and wheat consumption is of the same order as that in Western Europe. CD may therefore become more common in the future in these countries.


Image thanks to commons.wikimedia