IBS study

CrohnsWe recently came across an article from medicalxpress.com titled, “Researchers describe new form of irritable bowel syndrome.”

The latest in the world of more useless medical information has now given us a new form of IBS. This form is called Post-Diverticulitis IBS. Like all forms of Irritable Bowel Syndrome (IBS), this new IBS diagnosis offers no understanding of the cause of the IBS, nor a treatment plan to successfully cure it.

Excerpt from medicalxpress:

“We’ve known for a long time that after some people develop diverticulitis, they’re a different person. They experience recurrent abdominal pains, cramping and diarrhea that they didn’t have before,” Spiegel said. “The prevailing wisdom has been that once diverticulitis is treated, it’s gone. But we’ve shown that IBS symptoms occur after the diverticulitis, and it may result from an inflammatory process like a bomb going off in the body and leaving residual damage.”

Patients with diverticulitis have long known that they often have digestive problems when they do not have a diverticulitis flare-up. And doctors have long known this as well. Giving it a name changes absolutely nothing for the patient. However, it does create the potential to come up with drugs to target this now named disease, and the potential for other profitable procedures to be developed as well.

This may sound cynical, but it is how our medical system works. We come up with new names for old conditions, and then we pretend to treat them. No one in this article is addressing the cause of the problem, but they are patting themselves on the back for creating a new medical category.

Of course, there is a cause for this type of IBS, just as there is for all types of IBS. But in order to find it you have to work with an IBS specialist, someone who is looking at causes and not just treating symptoms.

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(image thanks to westvanhypnotherapy.com)

This is a nice article out of Germany on the relationship between the digestive problems in IBS (Irritable Bowel Syndrome) and IBD (Irritable Bowel Disease) and the bacteria present in the digestive tract.

However, this article is about the enzymes produced by those bacteria, not just about the bacteria. These enzymes do much more than digest food. They affect our immune system and our entire health. It’s a fascinating subject and it’s the first time that I’ve seen it addressed.

The article does not provide any immediate solutions, but it does open the conversation to a whole new way of understanding the significance of the bacteria found in our intestinal tract.

From National Institutes of Health:

Bacterial proteases in IBD and IBS

Proteases play a decisive role in health and disease. They fulfil diverse functions and have been associated with the pathology of gastrointestinal disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS).

The current knowledge focuses on host-derived proteases including matrix metalloproteinases, various serine proteases and cathepsins. The possible contribution of bacterial proteases has been largely ignored in the pathogenesis of IBD and IBS, although there is increasing evidence, especially demonstrated for proteases from pathogenic bacteria.

(more…)

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Another study on post infectious IBS. The immediate question is “Why does this happen?”  My suspicion is that it is because there are other factors already weakening the digestive tract. The infection was merely the straw that broke the camels back, so to speak.

It’s the other hidden issues that prevented some individuals from recovering, while everyone else did recover.  Our job is to find those issues so that people can recover.

Study:
Incidence of post-infectious irritable bowel syndrome and functional intestinal disorders following a water-borne viral gastroenteritis outbreak.

Source
Department of Medical and Surgical Sciences, Gastroenterology Unit, University and Spedali Civili of Brescia, Italy.

Abstract

OBJECTIVES:
Post-infectious irritable bowel syndrome (PI-IBS) may develop in 4-31% of affected patients following bacterial gastroenteritis (GE), but limited information is available on long-term outcome of viral GE. During summer 2009, a massive outbreak of viral GE associated with contamination of municipal drinking water (Norovirus) occurred in San Felice del Benaco (Lake Garda, Italy). To investigate the natural history of a community outbreak of viral GE, and to assess the incidence of PI-IBS and functional gastrointestinal disorders, we carried out a prospective population-based cohort study with a control group.

METHODS:
Baseline questionnaires were administered to the resident community within 1 month of the outbreak. Follow-up questionnaires of the Italian version of Gastrointestinal Symptom Rating Scale (GSRS, a 15-item survey scored according to a 7-point Likert scale) were mailed to all patients responding to baseline questionnaire at 3 and 6 months, and to a cohort of unaffected controls, living in the same geographical area, at 6 months after the outbreak. The GSRS item were grouped in five dimensions: abdominal pain, reflux, indigestion, diarrhea, and constipation. At month 12, all patients and controls were interviewed by a health assistant to verify Rome III criteria of IBS. Student’s t-test and χ(2)- or Fisher’s exact test were used as appropriate.

(more…)

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This Chinese study certainly seems to get it right.

From NIH.gov:

OBJECTIVE:
This study investigated the role of food intolerance in irritable bowel syndrome with diarrhoea (D-IBS).

METHODS:
Specific immunoglobulin G (IgG) antibodies against 14 common food antigens in the serum were measured in 77 patients with D-IBS and 26 healthy controls. Food-specific IgG antibodies were identified in 39 (50.65%) patients with D-IBS patients compared with four (15.38%) controls. For 12 weeks following the serological testing, 35 patients with D-IBS and food intolerance consumed diets that excluded the identified food. Changes in the main symptoms of D-IBS were evaluated before treatment and regularly during treatment in these patients.

RESULTS:
After 4 weeks’ dietary therapy, most symptoms of D-IBS had improved. By 12 weeks, all symptom scores had decreased significantly compared with the baseline scores.

CONCLUSIONS:
The 12-week specific-food exclusion diets resulted in significant improvements in abdominal pain (bloating level and frequency), diarrhoea frequency, abdominal distension, stool shape, general feelings of distress and total symptom score compared with baseline in patients with D-IBS.

Authors: Guo H, Jiang T, Wang J, Chang Y, Guo H, Zhang W.

Source
Department of Gastroenterology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.

Image thanks to redcedarwellness

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