Study Explores Connection Between Diet and Migraines

Published date: November 19, 2012 | Modified date: October 15, 2019

(Image thanks to annabrixthomsen.com)

Great study from National Institutes of Health.


Diet restriction in migraine, based on IgG against foods: A clinical double-blind, randomised, cross-over trial

Authors: Kadriye Alpay, Mustafa Ertaş, Elif Kocasoy Orhan, Didem Kanca Üstay, Camille Lieners, and Betül Baykan

Introduction:
It is well-known that specific foods trigger migraine attacks in some patients. We aimed to investigate the effect of diet restriction, based on IgG antibodies against food antigens on the course of migraine attacks in this randomised, double blind, cross-over, headache-diary based trial on 30 patients diagnosed with migraine without aura.

Methods:
Following a 6-week baseline, IgG antibodies against 266 food antigens were detected by ELISA. Then, the patients were randomised to a 6-week diet either excluding or including specific foods with raised IgG antibodies, individually. Following a 2-week diet-free interval after the first diet period, the same patients were given the opposite 6-week diet (provocation diet following elimination diet or vice versa). Patients and their physicians were blinded to IgG test results and the type of diet (provocation or elimination). Primary parameters were number of headache days and migraine attack count. Of 30 patients, 28 were female and 2 were male, aged 19–52 years (mean, 35±10 years).

Results:
The average count of reactions with abnormally high titre was 24±11 against 266 foods. Compared to baseline, there was a statistically significant reduction in the number of headache days (from 10.5±4.4 to 7.5±3.7; P<0.001) and number of migraine attacks (from 9.0±4.4 to 6.2±3.8; P<0.001) in the elimination diet period.

Conclusion:
This is the first randomised, cross-over study in migraineurs, showing that diet restriction based on IgG antibodies is an effective strategy in reducing the frequency of migraine attacks.


Image thanks to annabrixthomsen.com

The Irritable Bowel Syndrome Solution

Download this eBook to learn:
1. What is IBS and How it is Diagnosed
2. Why Many Treatments Fail
3. How to Treat the Root Cause of IBS, Not Just the Symptoms
Download "The IBS Solution" Ebook
>
close-link

We Are Open!

However, all services are being provided via Zoom, telephone, and mail.  This is nothing new for us.  Due to a long history of successfully  operating this way (a service we've offered to out-of-towners for the last several years), we've decided to eliminate all unnecessary risk for the foreseeable future.

Do not wait to schedule your appointment or to get your supplements. Just give us a call and we'll schedule you with a doctor or ship you what you need. (Note: The physical office is closed, so please call rather than try to stop by.)